OpenMW has issues when running on Big Endian CPU
Currently, OpenMW is playable only on machines which have Little Endian CPUs (like 80x86 and compatibles). Main issue here is reading/writing Morrowind data files, especially ESM files.
(RM-564 from redmine: created on 2013-02-16 by Douglas Mencken, , closed on 2016-12-20 by nobody, duplicates #3849 (closed))